Differential Expression ofCandida albicansSecreted Aspartyl Proteinase and Phospholipase B Genes in Humans Correlates with Active Oral and Vaginal Infections
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چکیده
منابع مشابه
Differential expression of secretory aspartyl proteinase genes (SAP1-10) in oral Candida albicans isolates with distinct karyotypes.
Two karyotypes of oral Candida albicans isolates, named b and c, constituted >80% of a collection from healthy carriers (22 b and 16 c isolates) and oral candidiasis patients who were either infected (31 b and 16 c isolates) or uninfected (13 b and 38 c isolates) with human immunodeficiency virus (HIV). The prevalence of the b and c karyotypes within HIV-positive and HIV-negative patients, resp...
متن کاملQuantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis.
A quantitative real-time RT-PCR system was established to identify which secreted aspartyl proteinase (SAP) genes are most highly expressed and potentially contribute to Candida albicans infection of human epithelium in vitro and in vivo. C. albicans SC5314 SAP1-10 gene expression was monitored in organotypic reconstituted human epithelium (RHE) models, monolayers of oral epithelial cells, and ...
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چکیده ندارد.
In vivo analysis of secreted aspartyl proteinase expression in human oral candidiasis.
Secreted aspartyl proteinases are putative virulence factors in Candida infections. Candida albicans possesses at least nine members of a SAP gene family, all of which have been sequenced. Although the expression of the SAP genes has been extensively characterized under laboratory growth conditions, no studies have analyzed in detail the in vivo expression of these proteinases in human oral col...
متن کاملPost Antifungal Effect, Phospholipase and Aspartyl Proteinase Production of Candida Albicans Oral Isolates following Exposure to Chlorhexidine
No: 69 (Poster) Health and Hygiene 238 POST ANTIFUNGAL EFFECT, PHOSPHOLIPASE AND ASPARTYL PROTEINASE PRODUCTION OF CANDIDA ALBICANS ORAL ISOLATES FOLLOWING EXPOSURE TO CHLORHEXIDINE A.N.B. Ellepola*, B.K. Joseph, Z.U. Khan and J.A.M.S. Jayatilake Health Sciences Centre, Kuwait University, Kuwait Faculty of Dental Sciences, University of Peradeniya, Sri Lanka *[email protected] An important viru...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2003
ISSN: 0022-1899,1537-6613
DOI: 10.1086/376536